Request PDF on ResearchGate | Intérêt des acides biliaires dans la cholestase gravidique | Intrahepatic cholestasis during pregnancy is a risk factor for. La cholestase gravidique a été reliée à des critères de jugement maternels et fœtaux/néonatals indésirables. Du fait que la physiopathologie est mal comprise, . Interventions pour le traitement de la cholestase gravidique. This is not the most recent version of this Review. view the current version 24 June

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Cholestasis of pregnancy presents with pruritus, sometimes incapacitating, less frequently by jaundice.


The susceptibility is explained by polymorphisms of genes gravidiue hepatocytic transport proteins that are important for bile secretion. Journal page Archives Contents list. In forms with severe pruritus, early delivery by induced labor between 37 and 38 weeks may be necessary. Outline Masquer le plan. It is slightly more frequent during twin pregnancies.

Access to the full text of this article requires a subscription. Bile acids, Ursodeoxycholic acid, Prematurity, Pruritus.


La cholestase gravidique – EM|consulte

Besides disturbing pruritus, maternal prognosis is good. Top of the page – Article Outline.

If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. Gravity of the disease comes from the occurrence of fetal graviidique, in particular prematurity often induced by obstetrical teams and its pulmonary complications, and sudden intra-uterine fetal death.

Hépato-Gastro & Oncologie Digestive

Access to the PDF text. Liver tests are abnormal, with mainly an increase in serum transaminases and bile acids. As per the Law relating to information storage and personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of that law your personal data.

You can move this window by clicking on the headline. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted. Access to the text HTML. La cholestase gravidique Intrahepatic cholestasis of pregnancy. Its prevalence in France is of the order of 1 per pregnancies. Personal information regarding our website’s visitors, including their identity, is confidential. Treatment by the bile acid ursodeoxycholic acid improves pruritus and decreases the frequency of fetal complications, without side effects in the mother or baby.


The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties. Contact Help Who are we? Clinical signs and biochemical abnormalities normalize rapidly after delivery, cholextase most after 3 to 4 weeks.


If you want to subscribe to this journal, see our rates You can purchase this item in Pay Per View: The fravidique is probably due to susceptibility to estrogens and progesterone, whose serum concentration is elevated during pregnancy and which are cholestatic. Elle survient pendant le 2 e ou le 3 e trimestre de la grossesse. It occurs during the second or third trimester.