Merkel-cell carcinoma (MCC) is a rare and highly aggressive skin cancer, which, in most cases, is caused by the Merkel cell polyomavirus (MCPyV or MCV). Merkel cell carcinoma, also called neuroendocrine carcinoma of the skin or trabecular cancer, is a very rare type of skin cancer that forms when. Los hallazgos clínicos más característicos son el rápido crecimiento y la ausencia de dolor. Aunque el carcinoma de células de Merkel puede afectar cualquier.

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Infectious diseases — viral systemic diseases A80—B34— Regular self-examination of the skin should be done every month and a check once a year with a qualified dermatologist.

Case celulass A 72 year-old woman was seen in our clinic for a rapidly growing, nodular, erythematous skin lesion with a shiny surface Figs.

[Merkel cell carcinoma experience in a reference medical center.]

Cancer starts when cells begin to grow out of control. It has an infiltrative growth pattern and spreads by the lymphatic vessels and blood. A skin lesion in the right malar region, coinciding with the external location of the lesion, was the only finding.

The Journal of Pathology. Merkel cells; Merkel cancer; Skin cancer. Views Read Edit View history.

Barely 2, cases have been reported celullas the initial description. Merkel cells Merkel cells are thought to be a type of skin neuroendocrine cellbecause they share some features with nerve cells and hormone-making cells. Red Blanchable Erythema Generalized drug eruptions viral exanthems toxic erythema systemic lupus erythematosus.

Immunofluorescence carcinnoma and electronic microscopy allowed the cell of origin of this pathology to be identified in International Journal of Cancer.


Bone involvement was not observed. Tang C, Toker C. It is important to study the extension of the disease when the diagnosis is made. This page was last cxrcinoma on 28 Octoberat Please help improve this article either by rewriting the how-to content or by moving it to WikiversityWikibooks or Wikivoyage.

Merkel-cell carcinoma

In addition, the virus has a particular mutation only when found in cancer cells, but not when it is detected in healthy skin cells.

Because Merkel cells are a type of neuroendocrine cell, Merkel cell carcinoma MCC is also sometimes called neuroendocrine carcinoma of the skin. Immunosuppression can profoundly increase the odds of developing MCC. Cells in nearly any part of the body can become cancer, and can then dde to other parts of the body. Ann Surg Oncol Jan Cutaneous Merkel cell carcinoma. Journal of the American Academy of Dermatology. They are located in the epidermal basement layer and are said to be slow action mechanoreceptors.

Carcinoma cutáneo de células de Merkel: Presentación de un caso y revisión de la literatura

Nearly all MCCs start on the skin, but a very small portion start in other parts of the body, such as inside the nose or esophagus. Regression of the main lesion has been documented.

Palacios 1J. Other associated factors include: As ofMCC occurred 30 times more often in people with chronic lymphocytic leukemia and Epidermal nevi, neoplasms, cysts Integumentary neoplasia Rare cancers.

The typical cytological features include the triad: Inmunosupression and Merkel cell cancer. MuV Mumps Cytomegalovirus Cytomegalovirus esophagitis. Twelve months after surgery, a submandibular tumor was found during a scheduled follow- up visit; the FNAB revealed cervical metastasis of cutaneous Merkel cell carcinoma. Given the short evolution between the date of intervention with radiation therapy and the appearance of cervical metastasis, the disease probably was initially stage II with microscopic lymph node involvement.


This skin cancer occurs most often in Caucasians between 60 and 80 years of age, and its rate of incidence is about twice as high in males as in females. A clinical case of Merkel cell carcinoma of the face treated with surgery and radiotherapy is reported and the literature is reviewed. It has a pattern of d dissemination that favors the appearance of numerous satellite lesions. The incidence of MCC is increased in conditions with defective immune functions such as malignancy, HIV infection, and organ transplant patients, etc.

[Merkel cell carcinoma experience in a reference medical center.]

Merkel cell carcinoma in pediatric and young adult patients is rare but more likely to present at advanced stages based on US registry data”. In other projects Wikimedia Commons. They usually don’t hurt, but they’re fast-growing and can sometimes open up as ulcers or sores see Signs and Symptoms of Merkel Cell Carcinoma.

Merkel cell carcinoma Microcystic adnexal carcinoma Mucinous carcinoma Primary cutaneous adenoid cystic carcinoma Verrucous carcinoma Malignant mixed tumor. Merkel cell carcinoma was first described in by Toker, 1 who defined it as a trabecular cell carcinoma.